91178 Applications of Molecular Biology
6cp; 2hpw x 10wks (lectures, online and recorded), 3hpw x 5wks (bioinformatics, online), 3hpw x 4 wks (practical)Requisite(s): 91132 Molecular Biology 1
These requisites may not apply to students in certain courses. See access conditions.
Anti-requisite(s): 91335 Molecular Biology 2
Description
Applications of Molecular Biology aims to provide students with an appreciation of the organisation of eukaryotic genomes, providing a fundamental introduction to the 'omics' technologies, including genomics, transcriptomics and proteomics. Mechanisms by which gene expression is regulated, including transcriptional and epigenetic mechanisms are included, as well as the roles of RNA in gene expression. PCR and real time quantitative PCR technologies and their applications in measuring gene expression, are also covered. The subject also provides knowledge of the molecular mechanisms of gene therapy for the treatment of disease, as well as the use and application of microarray and next generation sequencing technologies in biology and medicine. Students are given an introduction to the various types of human genetic mutations that lead to disease and the mechanisms of their detection and identification. The importance of computational biology and bioinformatics for the analysis of molecular data is emphasised. The application of molecular biology for advancing human health is discussed throughout.
Detailed subject description.