91178 Applications of Molecular Biology6cp; 2hpw x 10wks (lectures, online), 3hpw x 5wks (bioinformatics, online), 3hpw x 4 wks (practical)
Requisite(s): 91132 Molecular Biology 1
These requisites may not apply to students in certain courses. See access conditions.
Anti-requisite(s): 91335 Molecular Biology 2
This subject aims to provide students with an appreciation of the structure and organisation of the eukaryotic genome, providing a fundamental introduction to the 'omics' technologies including genomics, transcriptomics and proteomics. The various mechanisms by which gene expression is regulated, including transcriptional, post-transcriptional and epigenetic mechanisms, as well as the roles of RNA are also covered. Knowledge of the molecular mechanisms of gene therapy for the treatment of disease, as well as the use and application of microarray and next generation sequencing technologies in biology and medicine are covered. This subject gives students an introduction to the various types of human genetic mutation that lead to disease and the mechanisms of their detection and identification. The importance of computational biology and bioinformatics for the analysis of molecular data is emphasised. The application of molecular biology for advancing human health is discussed throughout.
Detailed subject description.