University of Technology Sydney

91572 Proteomics

8cp; 11 x 2hpw, workshop; 1 x 20hpw, pratical
There are course requisites for this subject. See access conditions.
Anti-requisite(s): 91536 Proteomics

Description

Proteomics describes the study of the complete set of proteins (proteome) that is expressed at a given time in a cell, tissue, organ or organism. Modern proteomics involves the integration of a wide range of protein analysis tools and information technologies to reliably identify qualitative and quantitative changes in proteins and their abundance; for example, in the detection of altered protein isoform (proteoform) abundance associated with disease. This subject covers leading technologies for sample preparation, protein fractionation, gel-based and chromatography-based separation and mass spectrometry for protein identification, characterisation and quantification.

Students explore facets of experimental design and data analysis through self-directed learning tasks and facilitated workshop activities. They are introduced to the best practice sample preparation technologies for different sample types, such as micro-organisms, plants, mammalian tissue and fluids. Written and oral assessment tasks require students to undertake independent research of relevant literature. The practical component allows students, through practice-related learning, to understand the logic and methodology underpinning sample preparation, complex mixture fractionation, protein separations and mass spectrometry. Students demonstrate their practice-related learning through the completion of a small laboratory-based project which requires a publication-style report encompassing data analysis skills.


Detailed subject description.

Access conditions

Note: The requisite information presented in this subject description covers only academic requisites. Full details of all enforced rules, covering both academic and admission requisites, are available at access conditions and My Student Admin.